Chronic airway obstruction in children. Most common causes, diagnosis and Surgical and Endoscopic Treatment

Abstract

Introduction: Obstructive airway pathology in children may be congenital or acquired. Fortunately, it is a rare condition, but in most cases, it implies a diagnostic and therapeutic challenge. Endoscopic techniques have experienced in the last years a breakthrough in the treatment of these lesions, but open surgery still plays an important role. Objective: Our objective was to review the most frequent causes of obstruction of the central airway in the child, their diagnostic and current treatment status. Conclusions: Obstructive airway pathology in children requires immediate stabilization, detailed assessment, meticulous planning and individualized treatment. Management of patients with airway obstruction requires a close cooperation between specialists organized in multidisciplinary teams, whose main objective is the diagnosis and timely resolution of the various congenital malformations and acquired lesions that affect the larynx, trachea and bronchi. In many cases the decision of the treatment of choice is not easy. Selection of the most suitable treatment depends on the patient’s clinical situation and the anatomic type of stenosis. The surgeon must master all available techniques, to solve each specific situation.
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Antón-Pacheco JL, Cabezalí D, Tejedor R, López M, Luna C, Comas JV, de Miguel E. The role of airway stenting in pediatric tracheobronchial obstruction. Eur J Cardiothorac Surg. 2008;33(6):1069-75. https://doi.org/10.1016/j.ejcts.2008.01.034 PMid:18299200

Anton-Pacheco JL, Cano I, Comas J, Galletti L, Polo L, García A, et al. Management of congenital tracheal stenosis in infancy. Eur J Cardiothorac Surg. 2006;29(6):991–6. https://doi.org/10.1016/j.ejcts.2005.12.061 PMid:16675228

Antón-Pacheco JL, CanoI-García A, Martínez A, Cuadros J, Berchi FL. Patterns of management of congenital tracheal stenosis. J Pediatr Surg.2003; 38:1452-8. https://doi.org/10.1016/S0022-3468(03)00495-0

Antón-Pacheco JL, Luna C, García E, López M, Morante R, Tordable C, et al. Initial experience with a new biodegradable airway stent in children: is this the stent we were waiting for? Pediatr Pulmonol. 2016;51(6):607-12. https://doi.org/10.1002/ppul.23340 PMid:26584412

Antón-Pacheco JL. Paediatric bronchoscopy: from where we came from, to where we are going. An Pediatr (Barc). 2012; 77(4):223-5. https://doi.org/10.1016/j.anpedi.2012.07.006 PMid:22902949

Antón-Pacheco JL. Tracheobronchial stents in children. Semin Pediatr Surg. 2016; 25(3):179-85. https://doi.org/10.1053/j.sempedsurg.2016.02.011 PMid:27301605

Backer CL, Mavroudis C, Gerber ME, Holinger LD. Tracheal surgery in children: an 18-year review of four techniques. Eur J Cardiothorac Surg. 2001;19(6):777-84. https://doi.org/10.1016/S1010-7940(01)00736-9

Backer CL, Mavroudis C, Holinger LD. Repair of congenital tracheal stenosis. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2002;5:173-86. https://doi.org/10.1053/pcsu.2002.29718 PMid:11994878

Benjamin, B., Inglis, A.: Minor congenital laryngeal clefts: diagnosis and classification. Ann. Otol. Rhinol. Laryngol. 1989; 98:417-420. https://doi.org/10.1177/000348948909800603 PMid:2729823

Boardman SJ, Albert DM. Single-stage and multistage pediatric laryngotracheal reconstruction. Otolaryngol Clin North Am. 2008;41(5):947-58. https://doi.org/10.1016/j.otc.2008.04.002 PMid:18775344

Boogaard R1, Huijsmans SH, Pijnenburg MW, Tiddens HA, de Jongste JC, Merkus PJ. Tracheomalacia and bronchomalacia in children: incidence and patient characteristics. Chest. 2005;128:3391-7. https://doi.org/10.1378/chest.128.5.3391 PMid:16304290

Brigger MT, Hartnick CJ. Surgery for pediatric vocal cord paralysis: a meta-analysis. Otolaryngol. Head Neck Surg. 2002;126:349-55. https://doi.org/10.1067/mhn.2002.124185 PMid:11997772

Broeks IJ, Hermans DJ, Dassel AC, van der Vleuten CJ, van Beynum IM. Propranolol treatment in life-threatening airway hemangiomas: a case series and review of literature. Int J Pediatr Otorhinolaryngol. 2013;77(11):1791-800.
https://doi.org/10.1016/j.ijporl.2013.08.011 PMid:24074695

Cantrell JR, Guild HG. Congenital stenosis of the trachea. Am J Surg. 1964;108:297-305. https://doi.org/10.1016/0002-9610(64)90023-6

Chen, E, Inglis A. Bilateral Vocal Cord Paralysis in Children. Otolaryngol Clin N Am. 2008; 41:889-901.
https://doi.org/10.1016/j.otc.2008.04.003 PMid:18775340

Cohen, S.R.: Congenital glottic webs in children. A retrospective review of 51 patients. Ann. Otol. Rhinol. Laryngol. 1985; Suppl.121:2–16. https://doi.org/10.1177/00034894850940S601

De Trey LA, Dudley J, Ismail-Koch H, Durward A, Bellsham-Revell H, Blaney S, Hore I, Austin CB, Morrison GA. Treatment of severe tracheobronchomalacia: Ten year experience. Int J Pediatr Otorhinolaryngol. 2016;83:57-62. https://doi.org/10.1016/j.ijporl.2016.01.022 PMid:26968054

Dedo DD. Pediatric vocal cord paralysis. Laryngoscope. 1979;89:1378-84.
https://doi.org/10.1002/lary.5540890902
PMid:481043

Dyce O, McDonald-McGinn D, Kirschner RE, Zackai E, Young K, Jacobs IN. Otolaryngologic manifestations of the 22q11.2 deletion syndrome. Arch. Otolaryngol. Head Neck Surg. 2002;128:1408–12. https://doi.org/10.1001/archotol.128.12.1408 PMid:12479730

Elliott M1, Roebuck D, Noctor C, McLaren C, Hartley B, Mok Q, Dunne C, Pigott N, Patel C, Patel A, Wallis C. The management of congenital tracheal stenosis. Int J Pediatr Otorhinolaryngol. 2003; 67:183–92. https://doi.org/10.1016/j.ijporl.2003.08.023

Fayon M, Donato L. Tracheomalacia (TM) or bronchomalacia (BM) in children: conservative or invasive therapy. Arch Pediatr. 2010;17:97-104. https://doi.org/10.1016/j.arcped.2009.09.015 PMid:19892533

Fraga JC, Jennings RW, Kim PC. Pediatric tracheomalacia. Semin Pediatr Surg. 2016;25(3):156-64.
https://doi.org/10.1053/j.sempedsurg.2016.02.008 PMid:27301602

Freitag L1, Ernst A, Unger M, Kovitz K, Marquette CH. A proposed classification system of central airway stenosis. Eur Respir J. 2007; 30(1):7-12. https://doi.org/10.1183/09031936.00132804 PMid:17392320

Friedman EM, Vastola AP, McGill TJI, Healy GB. Chronic pediatric stridor: etiology and outcome. Laryngoscope. 1990;100:277-80.
https://doi.org/10.1288/00005537-199003000-00013 PMid:2308452

Goldberg S, Shatz A, Picard E, Wexler I, Schwartz S, Swed E, et al. Endoscopic findings in children with obstructive sleep apnea: effects of age and hypotonia. Pediatr Pulmonol. 2005; 40:205-10. https://doi.org/10.1002/ppul.20230 PMid:15957182

Herrera P, Caldarone C, Forte V, Campisi P, Holtby H, Chait P, et al. The current state of congenital tracheal stenosis. Pediatr Surg Int. 2007;23(11):1033-44. https://doi.org/10.1007/s00383-007-1945-3 PMid:17712567

Hewitt RJ, Butler CR, Maughan EF, Elliott MJ. Congenital tracheobronchial stenosis. Semin Pediatr Surg. 2016;25(3):144-9.
https://doi.org/10.1053/j.sempedsurg.2016.02.007 PMid:27301600

Holinger LD, Barnes DR, Smid LJ, Holinger PH. Laryngocele and saccular cysts. Ann. Otol. Rhinol. Laryngol. 1978;87,675–85.
https://doi.org/10.1177/000348947808700513 PMid:718065

Holinger LD, Konior RJ. Surgical management of severe laryngomalacia. Laryngoscope 1989; 99:136-42.
https://doi.org/10.1288/00005537-198902000-00004 PMid:2913424

Holinger LD. Congenital laryngeal anomalies. In: Holinger LD, Lusk RP, Green CG (Eds.) Pediatric Laryngology and Bronchoesophagology, Lippincott-Raven, Philadelphia/New York (1997). p. 139-42.

Holinger, P.H., Brown, W.T. Congenital webs, cysts, laryngoceles and other anomalies of the larynx. Ann. Otol. Rhinol. Laryngol. 1967;76:744-752. https://doi.org/10.1177/000348946707600402 PMid:6059212

Jennings RW, Hamilton TE, Smithers CJ, Ngerncham M, Feins N, Foker JE. Surgical approaches to aortopexy for severe tracheomalacia. J Pediatr Surg. 2014;49:66-70. https://doi.org/10.1016/j.jpedsurg.2013.09.036 PMid:24439583

Kusak B, Cichocka-Jarosz E, Jedynak-Wasowicz U, Lis G. Types of laryngomalacia in children: interrelationship between clinical course and comorbid conditions. Eur Arch Otorhinolaryngol. 2017;274(3):1577-1583. https://doi.org/10.1007/s00405-016-4334-5 PMid:27722899 PMCid:PMC5309268

Lando T, April MM, Ward RF. Minimally invasive techniques in laryngotracheal reconstruction. Otolaryngol Clin North Am. 2008;41(5):935-46. https://doi.org/10.1016/j.otc.2008.04.007 PMid:18775343

Lee KS1, Chen BN, Yang CC, Chen YC. CO2 laser supraglottoplasty for severe laryngomalacia: a study of symptomatic improvement. Int. J. Pediatr. Otorhinolaryngol. 2007; 71:889-5. https://doi.org/10.1016/j.ijporl.2007.02.010 PMid:17416423

McArdle J, Gildea T, Mehta A. Balloon bronchoplasty: Its indications, benefits and complications. J Bronchol. 2005;4:123–7.
https://doi.org/10.1097/01.laboratory.0000159783.34078.3d

Monnier P, Dikkers FG, Eckel H, Sittel C, Piazza C, Campos G, et al. Preoperative assessment and classification of benign laryngotracheal stenosis: a consensus paper of the European Laryngological Society. Eur Arch Otorhinolaryngol. 2015;272(10):2885-96. https://doi.org/10.1007/s00405-015-3635-4 PMid:25951790

Monnier P, George M, Monod ML, Lang F. The role of the CO2 laser in the management of laryngotracheal stenosis: a survey of 100 cases. Eur. Arch. Otorhinolaryngol. 2005;262:602-8. https://doi.org/10.1007/s00405-005-0948-8 PMid:16021463

Monnier P, Ikonomidis C, Jaquet Y, George M. Proposal of a new classification for optimising outcome assessment following partial cricotracheal resections in severe pediatric subglotticstenosis. Int J Pediatrotorhinolaryngol. 2009;73(9):1217–21. https://doi.org/10.1016/j.ijporl.2009.05.008 PMid:19493576

Myer CM, O'Connor DM, Cotton RT. Proposed grading system for subglottic stenosis based on endotracheal tube sizes. Ann Otol Rhinol Laryngol. 1994;103:319-23. https://doi.org/10.1177/000348949410300410 PMid:8154776

Nicolai T. Airway stents in children. Pediatr Pulmonol. 2008;43:330-44. https://doi.org/10.1002/ppul.20790 PMid:18286550

Parente Hernández A, García-Casillas MA, Matute JA, Ca-izo A, Laín A, Fanjul M, et al. ¿Es el estridor un síntoma banal en el lactante? An Pediatr (Barc). 2007; 66(6):559-65. https://doi.org/10.1157/13107389

Philippe Monnier. Pediatric Airway Surgery. Ductal Cysts, Saccular Cysts and Laryngoceles. Springer Heidelberg Dordrecht (London New York) 2011. p. 141-145. https://doi.org/10.1007/978-3-642-13535-4_11

Philippe Monnier. Pediatric Airway Surgery. Laryngeal and Tracheal Clefts. 6. Springer Heidelberg Dordrecht (London New York) 2011. p.147-5.

Philippe Monnier. Pediatric Airway Surgery. Laryngeal Web and Atresia. Springer Heidelberg Dordrecht (London New York) 2011. p. 125-31. https://doi.org/10.1007/978-3-642-13535-4_9

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Springer Heidelberg Dordrecht (London New York) 2011. Endoscopic Assessment of the Compromised Paediatric Airway. p. 77-99.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Preoperative Assessment, Indications for Surgery and Parental Counselling. Springer Heidelberg Dordrecht (London New York) 2011. p. 231-40.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Endoscopic Techniques for Laryngotracheal Stenosis. Springer Heidelberg Dordrecht (London New York) 2011. p. 241-56.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Laryngotracheoplasty and Laryngotracheal Reconstruction. Springer Heidelberg Dordrecht (London New York) 2011. p. 257-277.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Partial Cricotracheal Resection. Springer Heidelberg Dordrecht (London New York) 2011. p. 279-321.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Surgery for Laryngotracheal Stenosis. Springer Heidelberg Dordrecht (London New York) 2011. p. 231-79.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Congenital Tracheal Stenosis. Springer Heidelberg Dordrecht (London New York) 2011. p.167-75.

Philippe Monnier. Pediatric Airway Surgery. Management of Laryngotracheal Stenosis in Infants and Children. Congenital Subglottic Stenosis.Springer Heidelberg Dordrecht (London New York) 2011. p. 120-124.

Rahbar R, Chen JL, Rosen RL, Lowry KC, Simon DM, Perez JA, et al. Endoscopic repair of laryngeal cleft type I and type II: when and why? Laryngoscope 2009;119:1797–802. https://doi.org/10.1002/lary.20551 PMid:19554639

Sandu K, Monnier P. Cricotracheal resection. Otolaryngol Clin North Am. 2008;41(5):981-98. https://doi.org/10.1016/j.otc.2008.04.012 PMid:18775346

Sharma SD, Gupta SL, Wyatt M, Albert D, Hartley B. Safe balloon sizing for endoscopic dilatation of subglottic stenosis in children. J Laryngol Otol. 2017;131(3):268-72. https://doi.org/10.1017/S0022215117000081 PMid:28095939

Simpson BB, Ryan DP, Donahoe PK, Schnitzer JJ, Kim SH, Doody DP. Type IV laryngotracheoesophageal clefts: surgical management for long-term survival. J. Pediatr. Surg.1996; 31:1128–33. https://doi.org/10.1016/S0022-3468(96)90101-3

Torre M, Carlucci M, Speggiorin S, Elliott MJ, Aortopexy for the treatment of tracheomalacia in children: review of the literature. Ital J Pediatr. 2012;30:38:62.

Wiatrak BJ. Recurrent respiratory papillomatosis. In: Graham JM, Scadding JK, Bull PD. (Eds.) Pediatric ENT, Springer, Berlin Heidelberg (2008). p. 255-65.
Navazo-Eguía, A. I., & Antón-pacheco-sánchez, J. L. (2018). Chronic airway obstruction in children. Most common causes, diagnosis and Surgical and Endoscopic Treatment. Revista ORL, 9(1), 63–79. https://doi.org/10.14201/orl.15901

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Author Biographies

Ana Isabel Navazo-Eguía

,
SACYL. Burgos
JEFA DE SECCIÓN DEL SERVICIO DE OTORRINOLARINGOLOGÍA.

Juan Luis Antón-pacheco-sánchez

,
Salud Madrid. Hospital Universitario Doce de Octubre. Servicio de Cirugía Infantil. Madrid. España
UNIDAD MULTIDISCIPLINAR DE VIA AÉREA INFANTIL
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