Carcinomas atípicos de la laringe. Descripción de dos casos
Abstract Introduction and objective: 95% of the malignant neoplasm of the larynx are squamous carcinoma. Neuroendocrine carcinomas correspond to at least 1 % of laryngeal tumors. The supraglottic is the most frequent laryngeal localization. Diagnosis is based on histological and immunohistochemically characteristic. They are divided into four histological types, which have a different natural evolution and prognosis. Description: We present two cases of laryngeal neuroendocrine carcinomas. One of them belongs to a small cell neuroendocrine carcinoma and the other one to a large cell carcinoma, which diagnosis generated controversy.
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Deep NL, Ekbom DC, Hinni ML, Zarka MA, Patel SH. High-grade Neuroendocrine Carcinoma of the Larynx: The Mayo Clinic Experience. Ann Otol Rhinol Laryngol 2016;125(6):464-9. - https://doi.org/10.1177/0003489415619179. - PMid:26611246
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Hemalatha AL, Anoosha K, Amita K, Vijay S, Avadhani K. Primary Laryngeal Neuroedocrine Carcinoma- A Rare Entity with Deviant Clinical Presentation. J Clin Diagn Res. 2014;8(9):7-8.
Lewis J, Spence D, Chiosea S, Barnes L, Brandwein-Gensler M, El-Mofty S. Large Cell Neuroendocrine Carcinoma of the Larynx: Definition of an Entity. Head Neck. 2010;4(3):198-207. - https://doi.org/10.1007/s12105-010-0188-0. - PMid:20589486 PMCid:PMC2923306
Lewis JE, Barnes L, Tse LY, Hunt JL. Tumours of bone and cartilage. En: Barnes L, Eveson JW, Reichart P, Sidransky D(eds). Pathology and Genetics of Head and Neck Tumours. V9. United Kingdom: Oxford University Press;2005. Pp.156-7.
Marcos M, Landínez G, Martínez G, Moráis D. Carcinomas neuroendocrinos en ORL: Un diagnóstico difícil. Acta Otorrinolaringol Esp. 2011;62(1): 51-5. - https://doi.org/10.1016/S2173-5735(11)70009-6 - https://doi.org/10.1016/j.otorri.2010.02.013. - PMid:20403582
Pérez M, Polo R, Fragola C. Tumores malignos de la laringe. Libro virtual de formación en ORL, SEORL [Internet]. Capítulo 113: 1-17. Disponible en: http://seorl.net/libro-virtual/ [Citado el 29/04/2015].
Van Der Laan TP, Plaat BE, Van Der Laan BF, Halmos GB. Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta- analysis of 436 reported cases. Head Neck. 2015;37(5):707-15. - https://doi.org/10.1002/hed.23666. - PMid:24596175
Xu B, Chetty R, Pérez Ordo-ez B. Neuroendocrine Neoplasms of the Head and Neck: Some Suggestions for the New WHO Classification of the Head and Neck Tumors. Head Neck 2014;8(1):24-32. - https://doi.org/10.1007/s12105-014-0531-y. - PMid:24595420 PMCid:PMC3950384
Zhu Y, Gao L, Meng Y, Diao W, Zhu X, Li G, et al. Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 cases. BioMed Research International [Internet]. 2015 [citado 2 Jul 2015]. Disponible en: https://www.hindawi.com/journals/bmri/2015/832194/. [Citado el 12/10/2017].
Ferlito A, Silver CE, Bradford CR, Rinaldo A. Neuroendocrine neoplasms of the larynx: An overview. Head Neck 2009;31(12):1634-46. - https://doi.org/10.1002/hed.21162. - PMid:19536850
Hemalatha AL, Anoosha K, Amita K, Vijay S, Avadhani K. Primary Laryngeal Neuroedocrine Carcinoma- A Rare Entity with Deviant Clinical Presentation. J Clin Diagn Res. 2014;8(9):7-8.
Lewis J, Spence D, Chiosea S, Barnes L, Brandwein-Gensler M, El-Mofty S. Large Cell Neuroendocrine Carcinoma of the Larynx: Definition of an Entity. Head Neck. 2010;4(3):198-207. - https://doi.org/10.1007/s12105-010-0188-0. - PMid:20589486 PMCid:PMC2923306
Lewis JE, Barnes L, Tse LY, Hunt JL. Tumours of bone and cartilage. En: Barnes L, Eveson JW, Reichart P, Sidransky D(eds). Pathology and Genetics of Head and Neck Tumours. V9. United Kingdom: Oxford University Press;2005. Pp.156-7.
Marcos M, Landínez G, Martínez G, Moráis D. Carcinomas neuroendocrinos en ORL: Un diagnóstico difícil. Acta Otorrinolaringol Esp. 2011;62(1): 51-5. - https://doi.org/10.1016/S2173-5735(11)70009-6 - https://doi.org/10.1016/j.otorri.2010.02.013. - PMid:20403582
Pérez M, Polo R, Fragola C. Tumores malignos de la laringe. Libro virtual de formación en ORL, SEORL [Internet]. Capítulo 113: 1-17. Disponible en: http://seorl.net/libro-virtual/ [Citado el 29/04/2015].
Van Der Laan TP, Plaat BE, Van Der Laan BF, Halmos GB. Clinical recommendations on the treatment of neuroendocrine carcinoma of the larynx: A meta- analysis of 436 reported cases. Head Neck. 2015;37(5):707-15. - https://doi.org/10.1002/hed.23666. - PMid:24596175
Xu B, Chetty R, Pérez Ordo-ez B. Neuroendocrine Neoplasms of the Head and Neck: Some Suggestions for the New WHO Classification of the Head and Neck Tumors. Head Neck 2014;8(1):24-32. - https://doi.org/10.1007/s12105-014-0531-y. - PMid:24595420 PMCid:PMC3950384
Zhu Y, Gao L, Meng Y, Diao W, Zhu X, Li G, et al. Laryngeal Neuroendocrine Carcinomas: A Retrospective Study of 14 cases. BioMed Research International [Internet]. 2015 [citado 2 Jul 2015]. Disponible en: https://www.hindawi.com/journals/bmri/2015/832194/. [Citado el 12/10/2017].
Michelena-Trecu, M. A., Díaz De Cerio-Canduela, P., Preciado-López, J., & Lag-Asturiano, E. (2019). Carcinomas atípicos de la laringe. Descripción de dos casos. Revista ORL, 10(1), 73–78. https://doi.org/10.14201/orl.16927
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