Systematic review of cancer research treatments
Abstract
:ntroduction. Given the prevalence and socioeconomic impact of cancer, research in all its aspects is of vital importance, and it requires a prior evaluation of the available scientific information. Methods. A systematic review of information on investigational cancer treatments in Europe over the last ten years was carried out. Results. The investigations included can be classified and analyzed according to the type of study, type of cancer, type of treatment, aspects evaluated, geographic location and language of publication. The methodological quality of the included CTs was assessed according to the Jadad scale. Conclusions. Seven types of scientific investigations were analyzed. The majority were CT with a score ?3 (out of 5) on the Jadad scale. Most referred to breast and prostate cancers, and pharmacological and immunological treatments. Safety and efficacy were preferably studied. They were carried out mainly in regions of Central, Western and Southern Europe, and they were published in English
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Harbour R, Miller J. A new system for grading recommendations in evidence based guidelines. BMJ. 2001; 323(7308):334-336.
International Agency for Research on Cancer (IARC) [Internet]. Lyon: IARC [actualizado 2019; citado 02 Mar 2020]. Disponible en: https://www.iarc.fr/
Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996; 17:1-12.
World Health Organization (WHO). Global action plan for the prevention and control of noncommunicable diseases 2013-2020 [Internet]. 2013 [citado 02 mar 2020]. Disponible en: https://apps.who.int/iris/bitstream/handle/10665/94384/9789241506236_eng.pdf
World Health Organization (WHO). Health Topics: Cancer [Internet]. Lyon: WHO [actualizado 12 sep 2018; citado 02 mar 2020]. Disponible en: https://www.who.int/news-room/fact-sheets/detail/cancer
World Health Organization (WHO). Seventieth World Health Assembly: resolutions and decisions, annexes [Internet]. Geneva: WHO; 22-31 May 2017 [citado 02 mar 2020]. Disponible en: http://apps.who.int/gb/ebwha/pdf_files/WHA70-REC1/A70_2017_REC1-en.pdf#page=27
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