Evidence and recommendation. Does Harmonic Ultracision offer any advantage in thyroidectomy?
Abstract Introduction and objective: In a patient with thyroid disease [patient] undergoing thyroidectomy [intervention] is the technique performed with Harmonic Ultracision Focus® (HU) compared with conventional techniques (ligation, mono or bipolar electrocoagulation and Ligasure®) [comparison] safer [outcome]? Material and Methods: Literature search in PubMed databases, Cochrane Library and Scopus with the search strategy "(((((ultrasonic scalpel) OR harmonic)) AND thyroidectomy)) AND meta-analysis" was made. Results: Level of Evidence: Evidence of the advantage of using HU in thyroidectomy compared to other techniques is high on disposal of sutures, facilitating access to smaller spaces, reducing surgical time, reducing intraoperative and postoperative bleeding, reducing of transient hypoparathyroidism, reducing postoperative pain, reducing hospital stay and reducing costs. Conclusions: Recommendation: The recommendation of the use of HU in thyroidectomy facing other alternatives (conventional surgery / Ligasure®) is weak in favor because it reduces the incidence of laryngeal paralysis and is strongly in favor because it reduces operating time, intraoperative bleeding and postoperative drainage volumen. It also reduces the incidence of hypocalcemia, hospital staying and costs. The recommendation of the use of HU in thyroidectomy is strongly in favor.
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Cannizzaro MA, Borzì L, Lo Bianco S, Okatyeva V, Cavallaro A, Buffone A. Comparison between Focus Harmonic scalpel and other hemostatic techniques in open thyroidectomy: A systematic review and meta-analysis. Head Neck. 2016;38:1571-8. http://dx.doi.org/10.1002/hed.24449 PMid:27224745
Cheng H, Soleas I, Ferko NC, Clymer JW, Amaral JF. A systematic review and meta-analysis of Harmonic Focus in thyroidectomy compared to conventional techniques. Thyroid Res. 2015;8:15. http://dx.doi.org/10.1186/s13044-015-0027-1 PMid:26430471 PMCid:PMC4589949
Cheng H, Soleas IM, Ferko NC, Cameron CG, Clymer JW, Amaral JF. Hospital costs associated with thyroidectomy performed with a Harmonic device compared to conventional techniques: a systematic review and meta-analysis. J. Med. Econ. 2016;1-9. http://dx.doi.org/10.3111/13696998.2016.1168826 PMid:26999563
Contin P, Gooßen K, Grummich K, Jensen K, Schmitz-Winnenthal H, Büchler MW, et al. ENERgized vessel sealing systems versus CONventional hemostasis techniques in thyroid surgery--the ENERCON systematic review and network meta-analysis. Langenbecks Arch. Surg. 2013;398:1039-56. http://dx.doi.org/10.1007/s00423-013-1137-7 PMid:24240627
Ecker T, Carvalho AL, Choe J-H, Walosek G, Preuss KJ. Hemostasis in thyroid surgery: harmonic scalpel versus other techniques--a meta-analysis. Otolaryngol Head Neck Surg. 2010;143:17-25. http://dx.doi.org/10.1016/j.otohns.2010.03.018 PMid:20620614
Garas G, Okabayashi K, Ashrafian H, Shetty K, Palazzo F, Tolley N, et al. Which hemostatic device in thyroid surgery? A network meta-analysis of surgical technologies. Thyroid. 2013;23:1138-50. http://dx.doi.org/10.1089/thy.2012.0588 PMid:23470035
Krones CJ, Conze J, Hoelzl F, Stumpf M, Klinge U, Moeller M, et al. Chemical composition of surgical smoke produced by electrocautery, harmonic scalpel and argon beaming - a short study. Eur. Surg. 2007;39:118-21. http://dx.doi.org/10.1007/s10353-006-0305-1
Melck AL, Wiseman SM. Harmonic scalpel compared to conventional hemostasis in thyroid surgery: a meta-analysis of randomized clinical trials. Int. J Surg Oncol 2010;2010:396079.
Pardal Refoyo J. Aspectos prácticos para la mejora de la seguridad del paciente en cirugía de tiroides y paratiroides. Rev Soc Otorrinolaringol Castilla Leon Cantab La Rioja. 2015;6:S50-72. Disponible en: http://hdl.handle.net/10366/125711. [Citado el 18 de junio de 2016].
Revelli L, Damiani G, Bianchi CBNA, Vanella S, Ricciardi W, Raffaelli M, et al. Complications in thyroid surgery. Harmonic Scalpel, Harmonic Focus versus Conventional Hemostasis: A meta-analysis. Int. J. Surg. Lond. Engl. 2016;28 Suppl 1:S22-32. http://dx.doi.org/10.1016/j.ijsu.2015.12.050 PMid:26768409
Cheng H, Soleas I, Ferko NC, Clymer JW, Amaral JF. A systematic review and meta-analysis of Harmonic Focus in thyroidectomy compared to conventional techniques. Thyroid Res. 2015;8:15. http://dx.doi.org/10.1186/s13044-015-0027-1 PMid:26430471 PMCid:PMC4589949
Cheng H, Soleas IM, Ferko NC, Cameron CG, Clymer JW, Amaral JF. Hospital costs associated with thyroidectomy performed with a Harmonic device compared to conventional techniques: a systematic review and meta-analysis. J. Med. Econ. 2016;1-9. http://dx.doi.org/10.3111/13696998.2016.1168826 PMid:26999563
Contin P, Gooßen K, Grummich K, Jensen K, Schmitz-Winnenthal H, Büchler MW, et al. ENERgized vessel sealing systems versus CONventional hemostasis techniques in thyroid surgery--the ENERCON systematic review and network meta-analysis. Langenbecks Arch. Surg. 2013;398:1039-56. http://dx.doi.org/10.1007/s00423-013-1137-7 PMid:24240627
Ecker T, Carvalho AL, Choe J-H, Walosek G, Preuss KJ. Hemostasis in thyroid surgery: harmonic scalpel versus other techniques--a meta-analysis. Otolaryngol Head Neck Surg. 2010;143:17-25. http://dx.doi.org/10.1016/j.otohns.2010.03.018 PMid:20620614
Garas G, Okabayashi K, Ashrafian H, Shetty K, Palazzo F, Tolley N, et al. Which hemostatic device in thyroid surgery? A network meta-analysis of surgical technologies. Thyroid. 2013;23:1138-50. http://dx.doi.org/10.1089/thy.2012.0588 PMid:23470035
Krones CJ, Conze J, Hoelzl F, Stumpf M, Klinge U, Moeller M, et al. Chemical composition of surgical smoke produced by electrocautery, harmonic scalpel and argon beaming - a short study. Eur. Surg. 2007;39:118-21. http://dx.doi.org/10.1007/s10353-006-0305-1
Melck AL, Wiseman SM. Harmonic scalpel compared to conventional hemostasis in thyroid surgery: a meta-analysis of randomized clinical trials. Int. J Surg Oncol 2010;2010:396079.
Pardal Refoyo J. Aspectos prácticos para la mejora de la seguridad del paciente en cirugía de tiroides y paratiroides. Rev Soc Otorrinolaringol Castilla Leon Cantab La Rioja. 2015;6:S50-72. Disponible en: http://hdl.handle.net/10366/125711. [Citado el 18 de junio de 2016].
Revelli L, Damiani G, Bianchi CBNA, Vanella S, Ricciardi W, Raffaelli M, et al. Complications in thyroid surgery. Harmonic Scalpel, Harmonic Focus versus Conventional Hemostasis: A meta-analysis. Int. J. Surg. Lond. Engl. 2016;28 Suppl 1:S22-32. http://dx.doi.org/10.1016/j.ijsu.2015.12.050 PMid:26768409
Pardal-Refoyo, J. L. (2016). Evidence and recommendation. Does Harmonic Ultracision offer any advantage in thyroidectomy?. Revista ORL, 7(4), 237–241. https://doi.org/10.14201/orl.14804
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