Changes in mucosa laryngopharyngeal vascularization after radiotherapy and concomitant chemotherapy observed with narrow band imaging. Description of two cases

  • Eulalia Carmen Porras-Alonso
    Hospital Universitario Puerto Real eporrasalonso[at]gmail.com
  • Carmen Salom-Coveñas
    Hospital Universitario Puerto Real
  • Lucia Gutiérrez-Bayard
    Hospital Universitario Puerta del Mar.
  • Miguel García-Teno
    Hospital Universitario Puerto Real

Abstract

Introduction and objective: Narrow Band Imaging (NBI) is an image enhancement system used to detect vascular anomalies in the mucosa and submucosa of neoplasms. In 2011 Ni established the five types of imaging patterns in the laryngeal mucosa relating them to the histopathological findings of the lesions. However, these patterns are modified by previous treatments of laser surgery, radiotherapy and chemotherapy. Our objective is to describe the NBI type images obtained in patients treated with the therapeutic regimen of radiotherapy and concomitant chemotherapy. Description: NBI images in a 68-year-old patient with stage III supraglottic non-keratinizing squamous cell carcinoma treated with radiotherapy and concomitant chemotherapy at three months and the year after treatment. NBI images in a 50-year-old patient with stage II nasopharynx non-keratinizing squamous cell carcinoma treated with radiotherapy and concomitant chemotherapy at three months and the year after treatment. Results: The obtained patterns are not identified with any of those previously established by Ni. The images differ depending on the time elapsed since the treatment. Conclusions: It is important to know the alterations observed in the mucosa and submucosa of patients treated with radiotherapy and concomitant chemotherapy since they differ from the characteristic patterns described by Ni associated with the presence of neoplasia.
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American Joint Committee on Cancer (AJCC) TNM Staging System. 7th edition. New York: Springer, 2010.

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Porras-Alonso, E. C., Salom-Coveñas, C., Gutiérrez-Bayard, L., & García-Teno, M. (2019). Changes in mucosa laryngopharyngeal vascularization after radiotherapy and concomitant chemotherapy observed with narrow band imaging. Description of two cases. Revista ORL, 10(1), 83–87. https://doi.org/10.14201/orl.17033

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