Hypoparathyroidism in the child
Abstract Hipoparathyroidism occurs when parathyroid hormone (PTH) is insufficient because of destruction of the parathyroid glands, abnormal parathyroid gland development or altered regulation of PTH production through calcium-sensing receptor (CaSR). Etiology and clinical features depend on the age of the patient. The goals of therapy are to maintain the serum calcium concentration in the low-normal range to prevent iatrogenic development of kidney stones. In this review, we will pay attention to the peculiriaties in the pediatric age.
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Lopes MP, Kliemann BS, Bini IB, et al. Hypoparathyroidism and pseudohypoparathyroidism: etiology, laboratory features and complications. Arch Endocrinol Metab 2016; 60: 532.
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Rastogi R, Beauchamp NJ, Ladenson PW. Calcification of the basal ganglia in chronic hypoparathyroidism. J Clin Endocrinol Metab 2003; 88: 1476.
Rajendram R, Deane JA, Barnes M, et al. Rapid onset childhood cataracts leading to the diagnosis of autoinmune polyendocrinopathy-candidiasis-ectodermal dystrophy. Am J Ophtalmol 2003; 136: 951.
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Shane E, Rosen CJ, Mulder JE. Diagnostic approach to hypercalcemia. UpToDate. Dec. 2021. Topic 836 Version 17.0.
López Úbeda M, de Arriba Muñoz A, Guerrero Fernández J, Sánchez Holgado M. Hipoparatiroidismo y pseudohipoparatiroidismo. Manual de diagnóstico y Terapeútica de Endocrinología Pediátrica. 2019
Rastogi R, Beauchamp NJ, Ladenson PW. Calcification of the basal ganglia in chronic hypoparathyroidism. J Clin Endocrinol Metab 2003; 88: 1476.
Rajendram R, Deane JA, Barnes M, et al. Rapid onset childhood cataracts leading to the diagnosis of autoinmune polyendocrinopathy-candidiasis-ectodermal dystrophy. Am J Ophtalmol 2003; 136: 951.
Kinirons MJ, Glasgow JF. The chronology of dentinal defects related to medical findings in hypoparathyroidism. J Dent 1985; 13: 346.
Shane E, Rosen CJ, Mulder JE. Diagnostic approach to hypercalcemia. UpToDate. Dec. 2021. Topic 836 Version 17.0.
Martín-Alonso, M., & Bajo Delgado, A. F. (2022). Hypoparathyroidism in the child. Revista ORL, 13(3), e27470. https://doi.org/10.14201/orl.27470
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