Simulation of Fermentation Pathway Using Bees Algorithm

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ISSN online: 2255-2863

Prefijo Doi: 10.14201

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Yi Ying Leong
Universiti Teknologi Malaysia
Malaysia
Chuii Khim Chong
Universiti Teknologi Malaysia
Malaysia
Lian En Chai
Universiti Teknologi Malaysia
Malaysia
Safaai Deris
Universiti Teknologi Malaysia
Malaysia
Rosli Illias
Universiti Teknologi Malaysia
Malaysia
Sigeru Omatu
Osaka Institute of Technology
Japan
Mohd Saberi Mohamad
Universiti Teknologi Malaysia
Malaysia
Vol. 1 No. 2 (2012), Articles, pages 13-19
DOI: https://doi.org/10.14201/ADCAIJ2012121319
Accepted: Jul 1, 2013
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Abstract

In this paper, we propose Bees Algorithm (BA) to enhance the performance in estimating the parameters for metabolic pathway data to simulate fermentation pathway for Saccharomyces cerevisiae. However, the parameter estimation of biological processes has always been a challenging task due to the complexity and nonlinear equations. Therefore, we present this algorithm as a new approach for parameter estimation for biological interactions to obtain more accurate parameter values. The result shows that BA outperforms other estimation algorithms as it produces the most accurate kinetic parameters, which contributes to the precision of simulated kinetic model.

Keywords:

Parameter Estimation, Bees Algorithm, Simulation, Saccharomyces cerevisiae, Glucose, Glucose-6-Phosphate, Fermentation Pathway

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References

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