Design and evaluation of cosmetics with apple vinegar and extract
Abstract
Apple cider vinegar is composed, largely by polyphenolic compounds, which give it a series of optimal characteristics for skin care, among which are the antioxidant, antimelanogenic, anti-cellulite, seborregulatory or anti-inflammatory activity. These properties are accentuated in the apple extract because it has a superior phenolic profile.
Four cosmetic formulations (two anti-wrinkle creams, one sebum-regulating cream and one anti-cellulite gel) were added by adding the vinegar or the extract, depending on the desired effect and cosmeticity, to a base previously selected and elaborated by emulsification or gelling techniques.
The results of the studies of conclusive combined stability, optimal for the four formulations, allowed to set an expiration of 24 months, which makes feasible its preparation and distribution at commercial level.
Based on all the studies carried out, it can be concluded that the incorporation of vinegar or apple extract in cosmetic formulas is an option to be taken into account, since it provides multiple benefits for the skin, does not present problems of incorporation into the bases and, its low cost, does not substantially increase the final formula
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Nusgens BV, Humbert P, Rougier A, Colige AC, Haftek M, Lambert CA, et al.Topically Applied Vitamin C Enhances the mRNA Level of Collagens I and III, Their Processing Enzymes and Tissue Inhibitor of Matrix Metalloproteinase 1 in the Human Dermis. J Invest Dermatol. 2001; 116(6): 853-9. - https://doi.org/10.1046/j.0022-202x.2001.01362.x
Olmos S. EMULSIONES (I). Panorama actual del medicamento. 2017; 41(402): 341-344.
Rodríguez R, Picinelli A, Suárez B. Phenolic profile of Asturian (Spain) natural cider. J Agric Food Chem. 2006; 54(1): 120-4. - https://doi.org/10.1021/jf051717e
Setorki M, Asgary S, Eidi A, Rohani AH, Esmaeil N. Effects of apple juice in risk factors of lipid porfile, inflamation and coagulation, endotelial markers and atherosclerotic lesions in high cholesterolemic rabbits. Lipids in Health and Disease. 2009; 8:39. - https://doi.org/10.1186/1476-511X-8-39
Sauermann K, Jaspers S, Koop U, Wenck H. Topically applied vitamin C increases the density of dermal papillae in aged human skin. BMC Dermatol. 2004; 4(1):13. - https://doi.org/10.1186/1471-5945-4-13
Shoaib HM, Akhtar N, Rasool F, Madni A, Saeed T, Khan BA, et al. Investigation of a New Sebum Control Cream Containing Apple Juice Extract. Asian Journal of Chemistry. 2011; 23(2):810-12.
Shoji T, Yamada M, Miura T, Nagashima K, Ogura K, Inagaki N, Maeda Yamamoto M. Chronic administration of apple polyphenols ameliorates hyperglycaemia in high-normal and borderline subjects: A randomised, placebo-controlled trial. Diabetes Res Clin Pract. 2017; 129: 43-51. - https://doi.org/10.1016/j.diabres.2017.03.028
Wu T, He M, Zang X, Zhou Y, Qiu T, Pan S, et al. A structure-activity relationship study of flavonoids as inhibitors of E. coli by membrane interaction effect. Biochimica et Biophysica Acta. 2013; 1828 (11): 2751-56. - https://doi.org/10.1016/j.bbamem.2013.07.029
Budak N. Bioactive components of Prunus avium L. black gold (red cherry) and Prunus avium L. stark gold (white cherry) juices, wines and vinegars.J Food Sei Technol. 2017; 54(1): 62-70. - https://doi.org/10.1007/s13197-016-2434-2
Dupont E, Journet M, Oula ML, Gomez J, Léveillé C, Loing E, Bilodeau D. An integral topical gel for cellulite reduction: results from a doublé-blind, randomized, placebo-controlled evaluation of efficacy. Clin Cosmet Investg Dermatol. 2014; 7: 73-88. - https://doi.org/10.2147/CCID.S53580
Dzialo M, Mierziak J, Korzun U, Preisner M, Szopa J, Kilma A. The Potential of Plant Phenolics in Prevention and Therapy of Skin Disorders. Int J Mol Sci. 2016; 17(2): 160. - https://doi.org/10.3390/ijms17020160
Guidelines on StabilityTtesting of Cosmetic Products. Cosmetics Europe- COLIPA. 2004.
Guyot S, Marnet N, Sanoner P, Drileau JF. Variability of the Polyphenolic Composition of Cider Apple (Malus domestica) Fruits and Juices. J Agric Food Chem. 2003; 51(21): 6240-7. - https://doi.org/10.1021/jf0301798
Matiz G, Osorio MR, Camacho F, Atencia M, Herazo J. Diseño y evaluación in vivo de fórmulas para acné basadas en aceites esenciales de naranja (Citrus sinensis), albahaca (Ocimum basilicum L) y ácido acético. Biomédica. 2012; 32: 126-33. - https://doi.org/10.7705/biomedica.v32i1.614
Nusgens BV, Humbert P, Rougier A, Colige AC, Haftek M, Lambert CA, et al.Topically Applied Vitamin C Enhances the mRNA Level of Collagens I and III, Their Processing Enzymes and Tissue Inhibitor of Matrix Metalloproteinase 1 in the Human Dermis. J Invest Dermatol. 2001; 116(6): 853-9. - https://doi.org/10.1046/j.0022-202x.2001.01362.x
Olmos S. EMULSIONES (I). Panorama actual del medicamento. 2017; 41(402): 341-344.
Rodríguez R, Picinelli A, Suárez B. Phenolic profile of Asturian (Spain) natural cider. J Agric Food Chem. 2006; 54(1): 120-4. - https://doi.org/10.1021/jf051717e
Setorki M, Asgary S, Eidi A, Rohani AH, Esmaeil N. Effects of apple juice in risk factors of lipid porfile, inflamation and coagulation, endotelial markers and atherosclerotic lesions in high cholesterolemic rabbits. Lipids in Health and Disease. 2009; 8:39. - https://doi.org/10.1186/1476-511X-8-39
Sauermann K, Jaspers S, Koop U, Wenck H. Topically applied vitamin C increases the density of dermal papillae in aged human skin. BMC Dermatol. 2004; 4(1):13. - https://doi.org/10.1186/1471-5945-4-13
Shoaib HM, Akhtar N, Rasool F, Madni A, Saeed T, Khan BA, et al. Investigation of a New Sebum Control Cream Containing Apple Juice Extract. Asian Journal of Chemistry. 2011; 23(2):810-12.
Shoji T, Yamada M, Miura T, Nagashima K, Ogura K, Inagaki N, Maeda Yamamoto M. Chronic administration of apple polyphenols ameliorates hyperglycaemia in high-normal and borderline subjects: A randomised, placebo-controlled trial. Diabetes Res Clin Pract. 2017; 129: 43-51. - https://doi.org/10.1016/j.diabres.2017.03.028
Wu T, He M, Zang X, Zhou Y, Qiu T, Pan S, et al. A structure-activity relationship study of flavonoids as inhibitors of E. coli by membrane interaction effect. Biochimica et Biophysica Acta. 2013; 1828 (11): 2751-56. - https://doi.org/10.1016/j.bbamem.2013.07.029
Sánchez Cueto, M., & Zarzuelo Castañeda, A. (2019). Design and evaluation of cosmetics with apple vinegar and extract. FarmaJournal, 4(2), 51–60. https://doi.org/10.14201/fj2019425160
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