Updating the Vaccination Schedule in Immigrants: Practical Aspects and Comparative Study about HBV
Abstract The HBV virus causes 4 million acute infections annually and 1 millon deaths due to complications such as cirrhosis and hepatocarcinoma. These complications arise mainly from chronic infection, which affects 90% of infected infants and 5% of adults. The HBV vaccine provides close to 100% protection and is given in three doses at 0, 1 and 6 months. This study analized vaccination coverage against hepatitis B in immingrant population, considering epidemiological factors and vaccination patterns, and was carried out within the “VacunApS” Project and in collaboration with the “Cruz Roja”. Participants were classified into vaccinated and unvaccinated, where the latter were offered serology to detect the presence of the HbsAg antigen and its antibodies. The results indicated that less than half of the immigrants were vaccinated, highligting that half of the unvaccinated came from Latin America. In addition, vaccination was more commun among children under 18 years old, and different administration patterns were noted due to the lack of a global vaccination schedule, concluding with the need to implement vaccination campaigns among the immigrant population.
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Asociación Española de Vacunología. Vacunas disponibles. [Internet]. Vacunas I Asociación Española de Vacunología; 2018. [Citado el 9 de septiembre de 2024]. Disponible en: https://vacunas.org/vacunas-disponibles-hepatitis-b/
Botero A, Londroño M, Navas M-C. Epidemiología y factores de riesgo de carcinoma hepatocelular. IATREIA. 2007; 20(1): 64-73.
Campbell C, et al. Risk factors for the development of hepatocellular carcinoma (HCC) in chronic hepatitis B virus infection: a systematic review and meta-analysis. Journal of Viral Heptitis. 2021; 28(3): 493-507.
Doyle M, Plaza J, Mateos F, Hoyos M del PS. Manejo del Niño Inmigrante: Calendario Vacunal. Revista Clínica de Medicina de Familia. 2009; 2(6): 294-9.
Fu J, Jiang J, Liu K. Metabolic síndrome and survival of patients with hepaticellular carcinoma: A meta-analysis. Frontiers in Oncology. 2023; 13.
INSST. Virus de la Hepatitis B- Virus- Agentes biológicos- Portal INSST [Internet]. 2021. [citado el 9 de septiembre de 2024]. Disponible en: https://www.insst.es/agentes-biologicos-basebio/virus/virus-de-la-hepatitis-b
Liang TJ. Hepatitis B: The virus and disease. Hepatology. 2009; 49(S5).
Llaneras J, et al. Etilogies and features of acute viral hepatitis in Spain. Clinical Gastroenterology and Hepatology. 2021; 19(5): 1030-7.
Ministerio de Sanidad. Áreas- Promoción de la salud y prevención- Vacunas y programas de vacunación- Hepatitis B- Ciudadanos- Vacunas. [Internet]. Gob.es; [citado el 9 de septiembre de 2024]. Disponible en: https://www.sanidad.gob.es/areas/promocionPrevencion/vacunaciones/vacunas/ciudadanos/hepatitisB.htm
Oviedo M, et al. The impact of immigration and vaccination in reducing the incidence of hepatitis B in Catalonia (Spain). BMC Public Health. 2012; 12(1):614.
Tripathi N, Mousa OY. Hepatitis B. StatPearls Publishing; 2023.
Conde, M., Vicente, B., Belhassen, M., Adserías, J., & Muro, A. (2025). Updating the Vaccination Schedule in Immigrants: Practical Aspects and Comparative Study about HBV. FarmaJournal, 10(1), 27–38. https://doi.org/10.14201/fj20251012738
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