Malaria proteomic research
Abstract Malaria is one of the main infectious diseases in the world, particularly in tropical and subtropical areas. Among the species that can cause this disease, in recent years P. vivax has been growing due to its own attributes, which make it highly difficult to eradicate.This study was focused on analyzing and identifying the proteome of P. vivax during the blood stage through a mass spectrometry analysis (LC-MS-MS).Results allowed us to identify 743 proteins, of which 522 never had been described before. Furthermore, the comparison of the expression of these proteins with P. vivax transcriptional profile allowed us to corroborate the adaptive change in the P. vivax VCG-1 strain transcriptome, previously described.
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Aurrecoechea C, Brestelli J, Brunk BP, Dommer J, Fischer S, Gajria B, Gao X, Gingle A, Grant G, Harb OS et al. PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res 2009; 37: D539-543.
Baird JK. Malaria caused by Plasmodium vivax: recurrent, difficult to treat, disabling, and threatening to life- averting the infectious bite preempts these hazards. Pathog Glob Health. 2013; 107(8): 475-9.
Bozdech Z, Mok S, Guangan H, Imwong M, Jaidee A et al. The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites. PNAS. 2008; 105(42): 16290-5.
Gething PW, Elyazar IRF, Moyes CL, Smith DL, Battle KE, et al. A Long Neglected World Malaria Map: Plasmodium vivax Endemicity in 2010. PLoS Negl Trop Dis. 2012; 6(9): e1814.
Howes RE, Patil AP, Piel FB, Nyangiri OA, Kabaria CW et al. The global distribution of the Duffy blood group. Nat Commun. 2011; 2: 266.
Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID Bioinformatics Resources. Nature Protoc. 2009; 4(1): 44-57. Disponible en: http://david.abcc.ncifcrf.gov/ [Último acceso 6 de junio de 2014].
Mendis K, Sina BJ, Marchesini P, Carter R. Neglected burden of Plasmodium vivax malaria. Am J Trop Med Hyg. 2001; 64(1,2): 97–106.
Moreno-Pérez DA, Ruíz JA, Patarroyo MA. Reticulocytes: Plasmodium vivax target cells. Biol Cell. 2013; 105: 251–260.
Price RN, Tjitra E, Guerra CA, Yeung S, White NJ et al. Vivax malaria: neglected and not bening. Am J Trop Med Hyg. 2007; 77(6 Suppl): 79–87.
Ray S, Renu D, Srivastava R, Gollapalli K, Taur S et al. Proteomic investigation of falciparum and vivax malaria for identification of surrogate protein markers. PLoS One. 2012; 7(8): e41751.
Roobsong W, Roytrakul S, Sattabongkot J, Li J, Udomsangpetch R et al. Determination of the Plasmodium vivax schizont stage proteome. J Proteomics. 2011; 74(9): 1701-10.
Westenberger SJ, McClean CM, Chattopadhyay R, Dharia NV, Carlton JM, et al. A syste1ms-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. PLoS Negl Trop Dis. 2010; 4(4): e653.
WHO. World malaria report 2013. WHO global malaria programme; 2013.
Arévalo-Herrera M, Chitnis C, Herrera S. Current status of Plasmodium vivax vaccine. Hum Vaccin. 2010; 6(1): 124-132.
Aurrecoechea C, Brestelli J, Brunk BP, Dommer J, Fischer S, Gajria B, Gao X, Gingle A, Grant G, Harb OS et al. PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res 2009; 37: D539-543.
Baird JK. Malaria caused by Plasmodium vivax: recurrent, difficult to treat, disabling, and threatening to life- averting the infectious bite preempts these hazards. Pathog Glob Health. 2013; 107(8): 475-9.
Bozdech Z, Mok S, Guangan H, Imwong M, Jaidee A et al. The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites. PNAS. 2008; 105(42): 16290-5.
Gething PW, Elyazar IRF, Moyes CL, Smith DL, Battle KE, et al. A Long Neglected World Malaria Map: Plasmodium vivax Endemicity in 2010. PLoS Negl Trop Dis. 2012; 6(9): e1814.
Howes RE, Patil AP, Piel FB, Nyangiri OA, Kabaria CW et al. The global distribution of the Duffy blood group. Nat Commun. 2011; 2: 266.
Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID Bioinformatics Resources. Nature Protoc. 2009; 4(1): 44-57. Disponible en: http://david.abcc.ncifcrf.gov/ [Último acceso 6 de junio de 2014].
Mendis K, Sina BJ, Marchesini P, Carter R. Neglected burden of Plasmodium vivax malaria. Am J Trop Med Hyg. 2001; 64(1,2): 97–106.
Moreno-Pérez DA, Ruíz JA, Patarroyo MA. Reticulocytes: Plasmodium vivax target cells. Biol Cell. 2013; 105: 251–260.
Price RN, Tjitra E, Guerra CA, Yeung S, White NJ et al. Vivax malaria: neglected and not bening. Am J Trop Med Hyg. 2007; 77(6 Suppl): 79–87.
Ray S, Renu D, Srivastava R, Gollapalli K, Taur S et al. Proteomic investigation of falciparum and vivax malaria for identification of surrogate protein markers. PLoS One. 2012; 7(8): e41751.
Roobsong W, Roytrakul S, Sattabongkot J, Li J, Udomsangpetch R et al. Determination of the Plasmodium vivax schizont stage proteome. J Proteomics. 2011; 74(9): 1701-10.
Westenberger SJ, McClean CM, Chattopadhyay R, Dharia NV, Carlton JM, et al. A syste1ms-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. PLoS Negl Trop Dis. 2010; 4(4): e653.
WHO. World malaria report 2013. WHO global malaria programme; 2013.
Morán, J., Moreno-Pérez, D. A., Patarroyo, M. A., & Muro, A. (2016). Malaria proteomic research. FarmaJournal, 1(1), 33–40. Retrieved from https://revistas.usal.es/cinco/index.php/2445-1355/article/view/13209
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